Abstract Low-coverage imputation is becoming ever more present in ancient DNA (aDNA) studies. Imputation pipelines commonly used for present-day genomes have been shown to yield accurate results when applied to ancient genomes. However. post-mortem damage (PMD). https://www.roneverhart.com/2-1-2-x-1-4-x-36-Smooth-Saddle-Threshold-NGP-410-36/