Interactions With Benzodiazepines and Other CNS Depressants Notify patients and caregivers that potentially deadly additive effects might arise if acetaminophen and codeine phosphate tablets are used with benzodiazepines or other CNS depressants, which include alcohol, instead of to use these drugs concomitantly Until supervised by a healthcare service provider (see https://codeine.store/is-codeine-an-opioid/